Blog

Modelling Cardiovascular Disease Mortality with PCSK9 Inhibitors Using a Synthetic Population

Our aim was to demonstrate how a synthetically generated sample of individuals could be used to populate clinical models. Our synthetic sample in this case was generated to match the risk factor variables in the 4S study sample, using similar distributions and correlation structure compared with the general population (as reported by the Health Survey for England).

Published: 18 Oct, 2018    Time to Read: 6 min(s) Read More»

Synthetic Sample Generation of the 4S Study Placebo Population Using a Stochastic Sampling Technique

We have successfully generated a synthetic sample of people whose group characteristics, such as mean age and gender, matched those of a real-life sample of people who took part in a clinical trial. This synthetic sample of people could be used to populate clinical or economic models, allowing for preliminary assessments of interventions with minimal costs.

Published: 18 Oct, 2018    Time to Read: 6 min(s) Read More»

How I use heoro.com: transforming targeted reviews

Targeted reviews have always been the inferior offering of the literature synthesis portfolio. Although relatively quick and inexpensive to produce, their methodology is usually more opaque than a full systematic review, leaving them vulnerable to bias in the studies selected for inclusion and therefore in the conclusions of the report.

Published: 08 Oct, 2018    Time to Read: 4 min(s) Read More»

Has life expectancy stalled?

You may have noticed in the news lately that the increases in life expectancy are ‘grinding to a halt’ in the UK. The Office for National Statistics in England and Wales has reported that improvements in life expectancy between 2015 and 2017 have stalled. The graph below shows the trend in life expectancy since 1838 showing there has been a consistent rise since the 1880s.

Published: 08 Oct, 2018    Time to Read: 5 min(s) Read More»

Help From Heoro.com: How to Find Economic Models for Bariatric Surgery

At ISPOR DC, we were asked how to find cost-effectiveness studies of bariatric surgery. Here's how to use heoro.com to answer that question.

Published: 29 Jun, 2016    Time to Read: 4 min(s) Read More»

Cost-utility Models in Cancer - Geographical Distribution

The heoro.com database can be used to rapidly identify economic models by geographical location. Here, we show the number of studies reporting cost-utility models in cancer by key jurisdictions, and discuss how well the focus of health economic research matches mortality data from each country.

Published: 28 Jun, 2016    Time to Read: 5 min(s) Read More»

Help From Heoro: How to Find Indirect Costs of Cancer Care in China

At ISPOR DC, we were asked whether we had any cost and resource use studies from China. Here's how to use heoro.com to find studies reporting indirect costs associated with cancer in China.

Published: 14 Jun, 2016    Time to Read: 3 min(s) Read More»

PRO Instruments added to the Heoro.com Database in June 2016

The new heoro.com database launched successfully at ispor dc with an ontology of the 4,250 pro tools identified from more than 22,200 pro study abstracts. In the two weeks since then, we've added another 18 instruments to the ontology.

Published: 14 Jun, 2016    Time to Read: 3 min(s) Read More»

Heoro.com PRO Instrument Ontology Has More Than 4,200 Items

The new heoro.com database launched successfully at ISPOR DC last week. We've developed an ontology of the 4,250 PRO tools we identified from more than 22,200 PRO study abstracts in the database.

Published: 30 May, 2016    Time to Read: 3 min(s) Read More»

Heoro.com Help: Has EORTC Been Mapped to Utility Values?

At ISPOR DC, we were asked "Has the EORTC tool been mapped to utility values in cancer?" Here's how to use heoro.com to answer that question.

Published: 30 May, 2016    Time to Read: 3 min(s) Read More»