Systematic Literature Reviews

We generate robust and detailed systematic literature reviews, with our online Evidence Mapper as an optional interim product.

Case Studies

A biotechnology company commissioned us to conduct a systematic literature review to assess the safety and efficacy of their product compared to various other surgical options. We followed the standard systematic literature review procedure and analysed the studies identified as relevant. The SLR highlighted our client’s product’s strengths compared to competitors, and the results were published in a peer-reviewed journal. Informed by the findings, the client had a better understanding of how to position their product among its peers within the market.
In response to regulatory requirements, a pharmaceutical company sought a full systematic literature review and clinical submission for their drug to be considered by the National Institute for Health and Care Excellence (NICE). Our comprehensive systematic literature review played a pivotal role in the successful submission. We then conducted a series of updates to the literature review to support HTA submissions and market access activities in different countries.

Systematic Literature Reviews are thorough and extensive reviews aiming to identify and assess all published literature on a topic of interest. Publications are screened at the abstract level by two researchers independently and any differences reconciled by the project manager or leader. The full text papers of all relevant studies are then retrieved for data extraction. The results are summarised in a detailed report suitable for a regulatory submission or journal publication.

Crystallise’s Evidence Mapper allows the quick and accurate dissemination of all the information on a topic based on the abstracts of relevant papers. This can be used as an intermediate step prior to full-text assessment and data extraction within a full systematic review.

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SS17 0HD



Company No: 7980921
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